Jordan Ayew, Jeffrey Schlupp, Wilfried Zaha and Cheikhou Kouyaté are some of the players scheduled to leave the club on service with their respective countries ahead of the 2021 African Nations Cup qualifying.
Ayew and Schlupp will both feature Ghana as the Black Stars take on Sudan in a doubleheader this month.
However, in the last international break, Ayew returned from international duty to Palace and tested positive for Covid19 and Hodgson called on the countries to take special care of the players.
“I am a little bit disappointed that players are going to go as far as Africa to play matches,” Hodgson said.
“I don’t know that in this COVID world and environment in which we live, it is great news to be sending your players to places like Sudan and Mauritius.
“But it is something that we probably have to do, but I am just hoping this time the countries that they go and play for will look after them well because the last time we lost Jordan Ayew for two weeks.